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High cholesterol can be a dangerous conditionTake the Cholesterol Quiz to understand what high cholesterol means in terms of.

Patients should be instructed to report symptoms of muscle painweaknessor tendernessIf such symptoms developcreatine kinase should be measuredand if elevatedsimvastatin should be discontinuedThe value of regular monitoring of creatine kinase is not knownIn some studieselevations in creatine kinase occurred in up to 5.2of patients on simvastatinIn most casesthese elevations were mildtransientand not associated with clinical symptomsRef]

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Simvastatin and rosuvastatin are used for reducing total cholesterolLDL cholesteroland triglyceridesand for increasing HDL cholesterolIn patients with coronary heart diseasediabetesperipheral vascular diseaseor history of stroke or other cerebrovascular diseaseZocor and Crestor are prescribed for reducing the risk of mortality by reducing death from coronary heart diseasereducing nonfatal myocardial infarctionheart attackand strokeand reducing the need for coronary and noncoronary revascularization procedures.

Statins typically are very similar to one anotherbut rosuvastatin is a bit of an outlierRosuvastatinaside from Lipitoratorvastatinis the most potent statin for lowering LDLIt’s different than simvastatin and many other statins in several important ways.

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